Welcome to the Nexus of Ethics, Psychology, Morality, Philosophy and Health Care

Welcome to the nexus of ethics, psychology, morality, technology, health care, and philosophy
Showing posts with label Science. Show all posts
Showing posts with label Science. Show all posts

Wednesday, August 12, 2020

Mental Health and Clinical Psychological Science in the Time of COVID-19: Challenges, Opportunities, and a Call to Action

June Gruber et al.
American Psychologist. 
Advance online publication.
http://dx.doi.org/10.1037/amp0000707

Abstract

COVID-19 presents significant social, economic, and medical challenges. Because COVID-19 has already begun to precipitate huge increases in mental health problems, clinical psychological science must assert a leadership role in guiding a national response to this secondary crisis. In this article, COVID-19 is conceptualized as a unique, compounding, multidimensional stressor that will create a vast need for intervention and necessitate new paradigms for mental health service delivery and training. Urgent challenge areas across developmental periods are discussed, followed by a review of psychological symptoms that likely will increase in prevalence and require innovative solutions in both science and practice. Implications for new research directions, clinical approaches, and policy issues are discussed to highlight the opportunities for clinical psychological science to emerge as an updated, contemporary field capable of addressing the burden of mental illness and distress in the wake of COVID-19 and beyond.

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Concluding Comments

Clinical psychological science is needed more than ever in response to both the acute and enduring psychological effects of COVID-19 (Adhanom Ghebreyesus, 2020). This article is intended to inspire dialogue surrounding the challenges the field faces and how it must adapt to meet the mental health demands of a rapidly evolving psychological landscape. Of course, sustained change will require strong advocacy to ensure that mental health research funding is available to understand and address mental health challenges following COVID-19. To secure a leadership role, clinical psychological scientists must be prepared to raise their voices not only within scientific outlets, but also in public discussions on the airwaves (radio, cable news), alongside colleagues in other scientific fields. Sustained effort, collaboration with other disciplines, and unity within psychology will be necessary to address the multifaceted impacts of COVID-19 on humanity.

Tuesday, August 11, 2020

What is herd immunity?

Joshua Krisch
Live Science
Originally published July 2020

Here is an excerpt:

Herd immunity doesn't always work

The ingredients for achieving herd immunity naturally are well understood. "You want a disease that is guaranteed to produce robust immunity with largely asymptomatic spread, and have a low R0," Altmann told Live Science. But even if the R0 is relatively high and most patients are symptomatic, herd immunity is still possible with an effective vaccine, and a vaccine program that immunizes the population en masse. "Think of our big, public-health vaccination success-stories: Smallpox and polio, both entirely due to massive, sustained vaccine programs with simple, highly effective vaccines," he said.

Robust immunity is necessary to ensure that those who become immune stay that way long enough for the pathogen to die out. Asymptomatic spread helps, because it means that fewer people are likely to die while the population waits for herd immunity to take hold — and increases the likelihood that there will be enough survivors to affect herd immunity in the first place. A low R0, of course, lowers the bar for how many individuals need to be immune before we see the infection rate flatten and decline.

Nonetheless, some diseases that are seemingly strong candidates for herd immunity never quite achieve it. Despite widespread infection and vaccination, chicken pox, for instance, has never been entirely eradicated from the population. That's because the virus that causes chicken pox remains latent in the nerve roots of those who are infected by it, even after they recover and acquire immunity to the disease. As once-infected individuals grow older their immune systems weaken and the virus can reactivate, causing shingles, which can, in turn, cause chicken pox.

"You might have eradicated chicken pox in a small island community, but then somebody's granny gets an attack of shingles and, over a matter of weeks, every kid on the island gets chicken pox," Hunter said. "You've achieved herd immunity, and [it appears] the virus has died out, but it's actually waiting to come out." Similar phenomena have been observed with tuberculosis, according to the WHO.

Vaccine-induced herd immunity can also fail when a vaccine results in only short-lived immunity within a population. Pertussis and mumps recently reappeared long after vaccine programs were assumed to have eradicated these diseases, and studies suggest that, while vaccine noncompliance played a role, the outbreaks were in part due to the vaccines losing effectiveness over time. "In the past few years we've had both pertussis and mumps outbreaks, and those have primarily resulted from waning immunity over time," Poland said.

The info is here.

Monday, August 10, 2020

Hydroxychloroquine RCTs: 'Ethically, the Choice Is Clear'

F. Perry Wilson
medscape.com
Originally poste 5 August 20

Here is an excerpt:

I am not going to say that HCQ has no effect on COVID-19. We can never be 100% sure of that. But I am sure that if it has an effect, it is quite small. Think of a world where HCQ was a miracle cure for COVID-19. Think how different all of these randomized trials would look. It would be immediately obvious.

Straight talk: HCQ is unlikely to kill you. It will kill someone (rare cases of torsades de pointes occur), but it is unlikely to be you or your patients. It really is a relatively well-tolerated drug. But there are adverse effects, as all of these trials show. And given that, our ethical obligation to "first, do no harm" is paramount here. There simply is not good evidence that HCQ has a robust effect, and there is evidence of at least moderate harm. Ethically, the choice is clear.

A few final caveats. Yes, only one of these trials reported on the use of zinc with HCQ (no effect, by the way). But two things on that particular issue: First, we know that many individuals take zinc supplements, so if, as the argument goes, HCQ is a miracle cure when given with zinc, you'd still see a benefit in an HCQ trial because a subset of people — maybe 25% — are taking zinc.

The zinc issue falls into this "no true Scotsman" land of HCQ studies. Any negative study can be dismissed: "Oh, you didn't give it early enough, or late enough, or with zinc, or with azithromycin, or on Sunday," or whatever. That's not how science works. I'm not saying that any of these studies are perfect, just that they are the best evidence we have right now. The burden of proof is to show that the drug works. Though I'm sure that pharma would be stoked to be able to argue that their latest negative trial can be ignored because their billion-dollar drug wasn't given in concert with vitamin C or whatever.

Yes, I know that another Yale professor is saying that HCQ can save lives.

And to those of you who have pointed out that he is a full professor while I am a mere associate professor, you really know how to hurt a guy. I have no idea why he wrote that article and didn't mention any of the randomized trials. But I embrace the academic freedom that he and I both have to present our best interpretation of the data.

The info is here.

Saturday, August 8, 2020

How behavioural sciences can promote truth, autonomy and democratic discourse online

Lorenz-Spreen, P., Lewandowsky,
S., Sunstein, C.R. et al.
Nat Hum Behav (2020).
https://doi.org/10.1038/s41562-020-0889-7

Abstract

Public opinion is shaped in significant part by online content, spread via social media and curated algorithmically. The current online ecosystem has been designed predominantly to capture user attention rather than to promote deliberate cognition and autonomous choice; information overload, finely tuned personalization and distorted social cues, in turn, pave the way for manipulation and the spread of false information. How can transparency and autonomy be promoted instead, thus fostering the positive potential of the web? Effective web governance informed by behavioural research is critically needed to empower individuals online. We identify technologically available yet largely untapped cues that can be harnessed to indicate the epistemic quality of online content, the factors underlying algorithmic decisions and the degree of consensus in online debates. We then map out two classes of behavioural interventions—nudging and boosting— that enlist these cues to redesign online environments for informed and autonomous choice.

Here is an excerpt:

Another competence that could be boosted to help users deal more expertly with information they encounter online is the ability to make inferences about the reliability of information based on the social context from which it originates. The structure and details of the entire cascade of individuals who have previously shared an article on social media has been shown to serve as proxies for epistemic quality. More specifically, the sharing cascade contains metrics such as the depth and breadth of dissemination by others, with deep and narrow cascades indicating extreme or niche topics and breadth indicating widely discussed issues. A boosting intervention could provide this information (Fig. 3a) to display the full history of a post, including the original source, the friends and public users who disseminated it, and the timing of the process (showing, for example, if the information is old news that has been repeatedly and artificially amplified). Cascade statistics teaches concepts that may take some practice to read and interpret, and one may need to experience a number of cascades to learn to recognize informative patterns.

Friday, August 7, 2020

Your Ancestors Knew Death in Ways You Never Will

Donald McNeil, Jr.
The New York Times
Originally posted 15 July 20

Here is the end:

As a result, New Yorkers took certain steps — sometimes very expensive and contentious, but all based on science: They dug sewers to pipe filth into the Hudson and East Rivers instead of letting it pool in the streets. In 1842, they built the Croton Aqueduct to carry fresh water to Manhattan. In 1910, they chlorinated its water to kill more germs. In 1912, they began requiring dairies to heat their milk because a Frenchman named Louis Pasteur had shown that doing so spared children from tuberculosis. Over time, they made smallpox vaccination mandatory.

Libertarians battled almost every step. Some fought sewers and water mains being dug through their properties, arguing that they owned perfectly good wells and cesspools. Some refused smallpox vaccines until the Supreme Court put an end to that in 1905, in Jacobson v. Massachusetts.

In the Spanish flu epidemic of 1918, many New Yorkers donned masks but 4,000 San Franciscans formed an Anti-Mask League. (The city’s mayor, James Rolph, was fined $50 for flouting his own health department’s mask order.) Slowly, science prevailed, and death rates went down.

Today, Americans are facing the same choice our ancestors did: We can listen to scientists and spend money to save lives, or we can watch our neighbors die.

“The people who say ‘Let her rip, let’s go for herd immunity’ — that’s just public-health nihilism,” said Dr. Joia S. Mukherjee, the chief medical office of Partners in Health, a medical charity fighting the virus. “How many deaths do we have to accept to get there?”

A vaccine may be close at hand, and so may treatments like monoclonal antibodies that will cut our losses.

Till then, we need not accept death as our overlord — we can simply hang on and outlast him.

The info is here.

Sunday, July 26, 2020

The trolley problem problem

James Wilson
aeon.com
Originally posted 20 May 20

Here is an excerpt:

Some philosophers think that ethical thought experiments either are, or have a strong affinity with, scientific experiments. On such a view, thought experiments, like other experiments, when well-designed can allow knowledge to be built via rigorous and unbiased testing of hypotheses. Just as in the randomised controlled trials in which new pharmaceuticals are tested, the circumstances and the types of control in thought experiments could be such as to make the situation very unlike everyday situations, but that is a virtue rather than a vice, insofar as it allows ethical hypotheses to be tested cleanly and rigorously.

If thought experiments are – literally – experiments, this helps to explain how they might provide insights into the way the world is. But it would also mean that thought experiments would inherit the two methodological challenges that attend to experiments more generally, known as internal and external validity. Internal validity relates to the extent to which an experiment succeeds in providing an unbiased test of the variable or hypothesis in question. External validity relates to the extent to which the results in the controlled environment translate to other contexts, and in particular to our own. External validity is a major challenge, as the very features that make an environment controlled and suitable to obtain internal validity often make it problematically different from the uncontrolled environments in which interventions need to be applied.

There are significant challenges with both the internal and the external validity of thought experiments. It is useful to compare the kind of care with which medical researchers or psychologists design experiments – including validation of questionnaires, double-blinding of trials, placebo control, power calculations to determine the cohort size required and so on – with the typically rather more casual approach taken by philosophers. Until recently, there has been little systematic attempt within normative ethics to test variations of different phrasing of thought experiments, or to think about framing effects, or sample sizes; or the extent to which the results from the thought experiment are supposed to be universal or could be affected by variables such as gender, class or culture. A central ambiguity has been whether the implied readers of ethical thought experiments should be just anyone, or other philosophers; and, as a corollary, whether judgments elicited are supposed to be expert judgments, or the judgments of ordinary human beings. As the vast majority of ethical thought experiments in fact remain confined to academic journals, and are tested only informally on other philosophers, de facto they are tested only on those with expertise in the construction of ethical theories, rather than more generally representative samples or those with expertise in the contexts that the thought experiments purport to describe.

The info is here.

Friday, May 29, 2020

Humans are complicated—do we need behavioral science to get through this?

Cathleen O'Grady
Ars Technica
Originally published 16 May 20

Here is an excerpt:

Leaning on the evidence

If humans didn’t insist on being quite so messily human, pandemic response would be much simpler. People would stay physically separated whenever possible; leaders would be proactive and responsive to evidence; our fight could be concentrated on the biomedical tools we so urgently need. The problem is that our maddening, imperfect humanity gets in the way at every turn, and getting around those imperfections demands that we understand the human behavior underlying them.

It's also clear that we need to understand the differences between groups of people to get a handle on the pandemic. Speculation has been rampant about how cultural differences might influence what sort of responses are palatable. And some groups are suffering disproportionately: death rates are higher among African-American and Latinx communities in the US, while a large analysis from the UK found that black, minority ethnic, and poorer people are at higher risk of death—our social inequalities, housing, transport, and food systems all play a role in shaping the crisis. We can’t extricate people and our complicated human behavior and society from the pandemic: they are one and the same.

In their paper, Van Bavel, Willer and their group of behavioral research proponents point to studies from fields like public health, sociology and psychology. They cover work on cultural differences, social inequality, mental health, and more, pulling out suggestions for how the research could be useful for policymakers and community leaders.

Those recommendations are pretty intuitive. For effective communications, it could be helpful to lean on sources that carry weight in different communities, like religious leaders, they suggest. And public health messaging that emphasizes protecting others—rather than fixating on just protecting oneself—tends to be persuasive, the proponents argue.

But not everyone is convinced that it would necessarily be a good idea to act on the recommendations. “Many of the topics surveyed are relevant,” write psychologist Hans IJzerman and a team of critics in their draft. The team's concern isn’t the relevance of the research; it’s how robust that research is. If there are critical flaws in the supporting data, then applying these lessons on a broad scale could be worse than useless—it could be actively harmful.

The info is here.

Thursday, May 28, 2020

Ethical road map through the COVID-19 pandemic

Zoe Fritz and others
BMJ 2020; 369
doi: https://doi.org/10.1136/bmj.m2033

The covid-19 pandemic has created profound ethical challenges in health and social care, not only for current decisions about individuals but also for longer term and population level policy decisions. Already covid-19 has generated ethical questions about the prioritisation of treatment, protective equipment, and testing; the impact of covid-19 strategies on patients with other health conditions; the approaches taken to advance care planning and resuscitation decisions; and the crisis in care homes.

Ethical questions continue to multiply as the pandemic progresses and new evidence emerges, including how best to distribute any new vaccines and treatments; how best to respond to evidence that disease severity and mortality are substantially greater in ethnic minority populations; how to prioritise patients for care as medical services re-open; how to manage assessment of immunity and its implications; and how the health system should be configured to manage any future peaks in cases.

Science and values

The UK government repeatedly states that it is “following the science” by heeding the advice provided through the Scientific Advisory Group for Emergencies (SAGE). However, this implies that the science alone will tell us what to do. Not only does this rhetoric shift the responsibility for difficult decisions on to “the science”, it is also wrong. Science may provide evidence on which to base decisions, but our values will determine what we do with that evidence and how we select the evidence to use. It is disingenuous and misleading to imply that value-free science leads the way. Both science and policy are value laden.

Values questions are being addressed primarily by professional organisations, although the UK government has independent advice, for example, from the Moral and Ethical Advisory Group. Despite such efforts to plot an ethical path, the current approach is piecemeal, confusing, and risks needless duplication of effort. Concerns are mounting about a lack of transparency around the ethical agenda underpinning decisions, a lack of coordination, and the absence of clear national leadership.

The info is here.

Wednesday, May 27, 2020

Trust in Medical Scientists Has Grown in U.S.

C. Funk, B. Kennedy, & C. Johnson
Pew Research Center
Originally published 21 May 20

Americans’ confidence in medical scientists has grown since the coronavirus outbreak first began to upend life in the United States, as have perceptions that medical doctors hold very high ethical standards. And in their own estimation, most U.S. adults think the outbreak raises the importance of scientific developments.

Scientists have played a prominent role in advising government leaders and informing the public about the course of the pandemic, with doctors such as Anthony Fauci and Deborah Birx, among others, appearing at press conferences alongside President Donald Trump and other government officials.

But there are growing partisan divisions over the risk the novel coronavirus poses to public health, as well as public confidence in the scientific and medical community and the role such experts are playing in public policy.

Still, most Americans believe social distancing measures are helping at least some to slow the spread of the coronavirus disease, known as COVID-19. People see a mix of reasons behind new cases of infection, including limited testing, people not following social distancing measures and the nature of the disease itself.

These are among the key findings from a new national survey by Pew Research Center, conducted April 29 to May 5 among 10,957 U.S. adults, and a new analysis of a national survey conducted April 20 to 26 among 10,139 U.S. adults, both using the Center’s American Trends Panel.

Public confidence in medical scientists to act in the best interests of the public has gone up from 35% with a great deal of confidence before the outbreak to 43% in the Center’s April survey. Similarly, there is a modest uptick in public confidence in scientists, from 35% in 2019 to 39% today. (A random half of survey respondents rated their confidence in one of the two groups.)

The info is here.

Monday, May 25, 2020

How Could the CDC Make That Mistake?

Alexis C. Madrigal & Robinson Meyer
The Atlantic
Originally posted 21 May 20

The Centers for Disease Control and Prevention is conflating the results of two different types of coronavirus tests, distorting several important metrics and providing the country with an inaccurate picture of the state of the pandemic. We’ve learned that the CDC is making, at best, a debilitating mistake: combining test results that diagnose current coronavirus infections with test results that measure whether someone has ever had the virus. The upshot is that the government’s disease-fighting agency is overstating the country’s ability to test people who are sick with COVID-19. The agency confirmed to The Atlantic on Wednesday that it is mixing the results of viral and antibody tests, even though the two tests reveal different information and are used for different reasons.

This is not merely a technical error. States have set quantitative guidelines for reopening their economies based on these flawed data points.

Several states—including Pennsylvania, the site of one of the country’s largest outbreaks, as well as Texas, Georgia, and Vermont—are blending the data in the same way. Virginia likewise mixed viral and antibody test results until last week, but it reversed course and the governor apologized for the practice after it was covered by the Richmond Times-Dispatch and The Atlantic. Maine similarly separated its data on Wednesday; Vermont authorities claimed they didn’t even know they were doing this.

The widespread use of the practice means that it remains difficult to know exactly how much the country’s ability to test people who are actively sick with COVID-19 has improved.

The info is here.

Tuesday, May 19, 2020

A pandemic plan was in place. Trump abandoned it - and science

Jason Karlawish
statnews.com
Originally posted 17 May 20

Here is an excerpt:

And then on Jan. 21, 2017, Donald Trump became president.

Beginning the morning after his inauguration, a spectacular science-related tragedy has unfolded. The Trump administration has systematically dismantled the executive branch’s science infrastructure and rejected the role of science to inform policy, essentially reversing both Republican and Democrat presidential administrations since World War II, when Vannevar Bush, an engineer, advised Presidents Franklin D. Roosevelt and Harry S. Truman.

President Trump’s pursuit of anti-science policy has been so effective that as the first cases of Covid-19 were breaking out in Wuhan, China, no meaningful science policy infrastructure was in place to advise him. As a consequence, America is suffering from a pandemic without a plan. Our responses are ineffectual and inconsistent. We are increasingly divided by misinformation and invidious messaging. And it’s not even over.

Facts will drive scientific decisions, not the other way around

On April 27, 2009, on the eve of his 100th day in office, Obama made a five-block trip from the White House to 2101 Constitution Ave. There, in the Great Hall of the National Academy of Sciences, he spoke about his administration’s commitment to science.

“Science is more essential for our prosperity, our security, our health, our environment, and our quality of life than it has ever been before,” he announced. He introduced the members of PCAST and explained how his administration would engage the scientific community directly in the work of public policy.

“I want to be sure that facts are driving scientific decisions — and not the other way around,” the president said. The audience broke into laughter.

Obama explained that his science advisers were already briefing him daily on the emerging threat of swine flu, which some were projecting could kill thousands of Americans.

The info is here.

Monday, March 9, 2020

The dangerous veneer of ‘science’

Regini Rini
Times Literary Supplement
Originally posted Feb 20

"Race science” seems to be the hideous new trend of 2020. Last month, an article in the journal Philosophical Psychology calling for greater investigation of purported genetic bases for racial IQ differences became the focus of intense academic controversy. Then came a new book, Human Diversity, from Charles Murray, prompting the New York Times columnist Jamelle Bouie to tweet: “i guess we’re gonna spend february arguing with phrenologists”. And then just this week, a twenty-seven-year-old consultant to the British government quickly resigned following media reports of his apparent musings on eugenics.

What’s going on? Why are we suddenly talking about this nonsense again? Donald Trump, and the winks he tosses to torch-wielding “blood and soil” marchers, may have something to do with it. Clearly there is a market for white coats who cater to white hoods. But the “race science” racket is growing, and we needn’t assume that all its practitioners have such transparently bigoted motives. Rather, I suspect that some are in it for the iconoclastic thrill of prodding at bien pensant pieties from behind the intellectual shield of capital-S Science.

There has always been a certain sort of mind that delights in saying whatever is verboten, from the Marquis de Sade to Christopher Hitchens. The writer George Packer worries that, in the high-stakes moral atmosphere of the Trump era, we no longer have cultural space for such fearless exploration of opinion. But I think this gets things exactly backwards. Trumpism is partly a result of the fact that it is now much easier to acquire an audience for heterodoxy. You don’t have to be a gifted essayist; you need only a Twitter account and lack of moral inhibition. Thoughtful iconoclasts aren’t silenced, they’re merely lost amid the din of so many icons being artlessly shattered.

The info is here.

Thursday, February 20, 2020

Harvey Weinstein’s ‘false memory’ defense is not backed by science

Anne DePrince & Joan Cook
The Conversation
Originally posted 10 Feb 20

Here is an excerpt:

In 1996, pioneering psychologist Jennifer Freyd introduced the concept of betrayal trauma. She made plain how forgetting, not thinking about and even mis-remembering an assault may be necessary and adaptive for some survivors. She argued that the way in which traumatic events, like sexual violence, are processed and remembered depends on how much betrayal there is. Betrayal happens when the victim depends on the abuser, such as a parent, spouse or boss. The victim has to adapt day-to-day because they are (or feel) stuck in that relationship. One way that victims can survive is by thinking or remembering less about the abuse or telling themselves it wasn’t abuse.

Since 1996, compelling scientific evidence has shown a strong relationship between amnesia and victims’ dependence on abusers. Psychologists and other scientists have also learned much about the nature of memory, including memory for traumas like sexual assault. What gets into memory and later remembered is affected by a host of factors, including characteristics of the person and the situation. For example, some individuals dissociate during or after traumatic events. Dissociation offers a way to escape the inescapable, such that people feel as if they have detached from their bodies or the environment. It is not surprising to us that dissociation is linked with incomplete memories.

Memory can also be affected by what other people do and say. For example, researchers recently looked at what happened when they told participants not to think about some words that they had just studied. Following that instruction, those who had histories of trauma suppressed more memories than their peers did.

The info is here.

Thursday, February 13, 2020

FDA and NIH let clinical trial sponsors keep results secret and break the law

Charles Piller
sciencemag.org
Originally posted 13 Jan 20

For 20 years, the U.S. government has urged companies, universities, and other institutions that conduct clinical trials to record their results in a federal database, so doctors and patients can see whether new treatments are safe and effective. Few trial sponsors have consistently done so, even after a 2007 law made posting mandatory for many trials registered in the database. In 2017, the National Institutes of Health (NIH) and the Food and Drug Administration (FDA) tried again, enacting a long-awaited “final rule” to clarify the law’s expectations and penalties for failing to disclose trial results. The rule took full effect 2 years ago, on 18 January 2018, giving trial sponsors ample time to comply. But a Science investigation shows that many still ignore the requirement, while federal officials do little or nothing to enforce the law.

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Contacted for comment, none of the institutions disputed the findings of this investigation. In all 4768 trials Science checked, sponsors violated the reporting law more than 55% of the time. And in hundreds of cases where the sponsors got credit for reporting trial results, they have yet to be publicly posted because of quality lapses flagged by ClinicalTrials.gov staff.

The info is here.

Friday, January 31, 2020

Most scientists 'can't replicate studies by their peers'

Test tubesTom Feilden
BBC.com
Originally posted 22 Feb 17

Here is an excerpt:

The authors should have done it themselves before publication, and all you have to do is read the methods section in the paper and follow the instructions.

Sadly nothing, it seems, could be further from the truth.

After meticulous research involving painstaking attention to detail over several years (the project was launched in 2011), the team was able to confirm only two of the original studies' findings.

Two more proved inconclusive and in the fifth, the team completely failed to replicate the result.

"It's worrying because replication is supposed to be a hallmark of scientific integrity," says Dr Errington.

Concern over the reliability of the results published in scientific literature has been growing for some time.

According to a survey published in the journal Nature last summer, more than 70% of researchers have tried and failed to reproduce another scientist's experiments.

Marcus Munafo is one of them. Now professor of biological psychology at Bristol University, he almost gave up on a career in science when, as a PhD student, he failed to reproduce a textbook study on anxiety.

"I had a crisis of confidence. I thought maybe it's me, maybe I didn't run my study well, maybe I'm not cut out to be a scientist."

The problem, it turned out, was not with Marcus Munafo's science, but with the way the scientific literature had been "tidied up" to present a much clearer, more robust outcome.

The info is here.

Friday, January 24, 2020

Psychology accused of ‘collective self-deception’ over results

Image result for psychology as scienceJack Grove
The Times Higher Education
Originally published 10 Dec 19

Here is an excerpt:

If psychologists are serious about doing research that could make “useful real-world predictions”, rather than conducting highly contextualised studies, they should use “much larger and more complex datasets, experimental designs and statistical models”, Dr Yarkoni advises.

He also suggests that the “sweeping claims” made by many papers bear little relation to their results, maintaining that a “huge proportion of the quantitative inferences drawn in the published psychology literature are so inductively weak as to be at best questionable and at worst utterly insensible”.

Many psychologists were indulging in a “collective self-deception” and should start “acknowledging the fundamentally qualitative nature of their work”, he says, stating that “a good deal of what currently passes for empirical psychology is already best understood as insightful qualitative analysis dressed up as shoddy quantitative science”.

That would mean no longer including “scientific-looking inferential statistics” within papers, whose appearance could be considered an “elaborate rhetorical ruse used to mathematicise people into believing claims they would otherwise find logically unsound”.

The info is here.

Friday, January 17, 2020

Consciousness is real

Image result for consciousnessMassimo Pigliucci
aeon.com
Originally published 16 Dec 19

Here is an excerpt:

Here is where the fundamental divide in philosophy of mind occurs, between ‘dualists’ and ‘illusionists’. Both camps agree that there is more to consciousness than the access aspect and, moreover, that phenomenal consciousness seems to have nonphysical properties (the ‘what is it like’ thing). From there, one can go in two very different directions: the scientific horn of the dilemma, attempting to explain how science might provide us with a satisfactory account of phenomenal consciousness, as Frankish does; or the antiscientific horn, claiming that phenomenal consciousness is squarely outside the domain of competence of science, as David Chalmers has been arguing for most of his career, for instance in his book The Conscious Mind (1996).

By embracing the antiscientific position, Chalmers & co are forced to go dualist. Dualism is the notion that physical and mental phenomena are somehow irreconcilable, two different kinds of beasts, so to speak. Classically, dualism concerns substances: according to René Descartes, the body is made of physical stuff (in Latin, res extensa), while the mind is made of mental stuff (in Latin, res cogitans). Nowadays, thanks to our advances in both physics and biology, nobody takes substance dualism seriously anymore. The alternative is something called property dualism, which acknowledges that everything – body and mind – is made of the same basic stuff (quarks and so forth), but that this stuff somehow (notice the vagueness here) changes when things get organised into brains and special properties appear that are nowhere else to be found in the material world. (For more on the difference between property and substance dualism, see Scott Calef’s definition.)

The ‘illusionists’, by contrast, take the scientific route, accepting physicalism (or materialism, or some other similar ‘ism’), meaning that they think – with modern science – not only that everything is made of the same basic kind of stuff, but that there are no special barriers separating physical from mental phenomena. However, since these people agree with the dualists that phenomenal consciousness seems to be spooky, the only option open to them seems to be that of denying the existence of whatever appears not to be physical. Hence the notion that phenomenal consciousness is a kind of illusion.

The essay is here.

Tuesday, December 17, 2019

We Might Soon Build AI Who Deserve Rights

Image result for robot rightsEric Schweitzengebel
Splintered Mind Blog
From a Talk at Notre Dame
Originally posted 17 Nov 19

Abstract

Within a few decades, we will likely create AI that a substantial proportion of people believe, whether rightly or wrongly, deserve human-like rights. Given the chaotic state of consciousness science, it will be genuinely difficult to know whether and when machines that seem to deserve human-like moral status actually do deserve human-like moral status. This creates a dilemma: Either give such ambiguous machines human-like rights or don't. Both options are ethically risky. To give machines rights that they don't deserve will mean sometimes sacrificing human lives for the benefit of empty shells. Conversely, however, failing to give rights to machines that do deserve rights will mean perpetrating the moral equivalent of slavery and murder. One or another of these ethical disasters is probably in our future.

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But as AI gets cuter and more sophisticated, and as chatbots start sounding more and more like normal humans, passing more and more difficult versions of the Turing Test, these movements will gain steam among the people with liberal views of consciousness. At some point, people will demand serious rights for some AI systems. The AI systems themselves, if they are capable of speech or speechlike outputs, might also demand or seem to demand rights.

Let me be clear: This will occur whether or not these systems really are conscious. Even if you’re very conservative in your view about what sorts of systems would be conscious, you should, I think, acknowledge the likelihood that if technological development continues on its current trajectory there will eventually be groups of people who assert the need for us to give AI systems human-like moral consideration.

And then we’ll need a good, scientifically justified consensus theory of consciousness to sort it out. Is this system that says, “Hey, I’m conscious, just like you!” really conscious, just like you? Or is it just some empty algorithm, no more conscious than a toaster?

Here’s my conjecture: We will face this social problem before we succeed in developing the good, scientifically justified consensus theory of consciousness that we need to solve the problem. We will then have machines whose moral status is unclear. Maybe they do deserve rights. Maybe they really are conscious like us. Or maybe they don’t. We won’t know.

And then, if we don’t know, we face quite a terrible dilemma.

If we don’t give these machines rights, and if turns out that the machines really do deserve rights, then we will be perpetrating slavery and murder every time we assign a task and delete a program.

The blog post is here.

Friday, December 6, 2019

Ethical research — the long and bumpy road from shirked to shared

Sarah Franklin
Nature.com
Originally posted October 29, 2019

Here is an excerpt:

Beyond bewilderment

Just as the ramifications of the birth of modern biology were hard to delineate in the late nineteenth century, so there is a sense of ethical bewilderment today. The feeling of being overwhelmed is exacerbated by a lack of regulatory infrastructure or adequate policy precedents. Bioethics, once a beacon of principled pathways to policy, is increasingly lost, like Simba, in a sea of thundering wildebeest. Many of the ethical challenges arising from today’s turbocharged research culture involve rapidly evolving fields that are pursued by globally competitive projects and teams, spanning disparate national regulatory systems and cultural norms. The unknown unknowns grow by the day.

The bar for proper scrutiny has not so much been lowered as sawn to pieces: dispersed, area-specific ethical oversight now exists in a range of forms for every acronym from AI (artificial intelligence) to GM organisms. A single, Belmont-style umbrella no longer seems likely, or even feasible. Much basic science is privately funded and therefore secretive. And the mergers between machine learning and biological synthesis raise additional concerns. Instances of enduring and successful international regulation are rare. The stereotype of bureaucratic, box-ticking ethical compliance is no longer fit for purpose in a world of CRISPR twins, synthetic neurons and self-driving cars.

Bioethics evolves, as does any other branch of knowledge. The post-millennial trend has been to become more global, less canonical and more reflexive. The field no longer relies on philosophically derived mandates codified into textbook formulas. Instead, it functions as a dashboard of pragmatic instruments, and is less expert-driven, more interdisciplinary, less multipurpose and more bespoke. In the wake of the ‘turn to dialogue’ in science, bioethics often looks more like public engagement — and vice versa. Policymakers, polling companies and government quangos tasked with organizing ethical consultations on questions such as mitochondrial donation (‘three-parent embryos’, as the media would have it) now perform the evaluations formerly assigned to bioethicists.

The info is here.

Monday, December 2, 2019

Neuroscientific evidence in the courtroom: a review.

Image result for neuroscience evidence in the courtroom"Aono, D., Yaffe, G. & Kober, H.
Cogn. Research 4, 40 (2019)
doi:10.1186/s41235-019-0179-y

Abstract

The use of neuroscience in the courtroom can be traced back to the early twentieth century. However, the use of neuroscientific evidence in criminal proceedings has increased significantly over the last two decades. This rapid increase has raised questions, among the media as well as the legal and scientific communities, regarding the effects that such evidence could have on legal decision makers. In this article, we first outline the history of neuroscientific evidence in courtrooms and then we provide a review of recent research investigating the effects of neuroscientific evidence on decision-making broadly, and on legal decisions specifically. In the latter case, we review studies that measure the effect of neuroscientific evidence (both imaging and nonimaging) on verdicts, sentencing recommendations, and beliefs of mock jurors and judges presented with a criminal case. Overall, the reviewed studies suggest mitigating effects of neuroscientific evidence on some legal decisions (e.g., the death penalty). Furthermore, factors such as mental disorder diagnoses and perceived dangerousness might moderate the mitigating effect of such evidence. Importantly, neuroscientific evidence that includes images of the brain does not appear to have an especially persuasive effect (compared with other neuroscientific evidence that does not include an image). Future directions for research are discussed, with a specific call for studies that vary defendant characteristics, the nature of the crime, and a juror’s perception of the defendant, in order to better understand the roles of moderating factors and cognitive mediators of persuasion.

Significance

The increased use of neuroscientific evidence in criminal proceedings has led some to wonder what effects such evidence has on legal decision makers (e.g., jurors and judges) who may be unfamiliar with neuroscience. There is some concern that legal decision makers may be unduly influenced by testimony and images related to the defendant’s brain. This paper briefly reviews the history of neuroscientific evidence in the courtroom to provide context for its current use. It then reviews the current research examining the influence of neuroscientific evidence on legal decision makers and potential moderators of such effects. Our synthesis of the findings suggests that neuroscientific evidence has some mitigating effects on legal decisions, although neuroimaging-based evidence does not hold any special persuasive power. With this in mind, we provide recommendations for future research in this area. Our review and conclusions have implications for scientists, legal scholars, judges, and jurors, who could all benefit from understanding the influence of neuroscientific evidence on judgments in criminal cases.