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Tuesday, December 21, 2021

The Most Common Pain Relief Drug in The World Induces Risky Behavior, Study Finds

Peter Dockrill
sciencealert.com
Originally published 18 NOV 21

Acetaminophen, also known as paracetamol and sold widely under the brand names Tylenol and Panadol, also increases risk-taking, according to a study published in 2020 that measured changes in people's behavior when under the influence of the common over-the-counter medication.

"Acetaminophen seems to make people feel less negative emotion when they consider risky activities – they just don't feel as scared," neuroscientist Baldwin Way from The Ohio State University explained last year.

"With nearly 25 percent of the population in the US taking acetaminophen each week, reduced risk perceptions and increased risk-taking could have important effects on society."

The findings add to a recent body of research suggesting that acetaminophen's effects on pain reduction also extend to various psychological processes, lowering people's receptivity to hurt feelings, experiencing reduced empathy, and even blunting cognitive functions.

Similarly, Way's study suggests people's affective ability to perceive and evaluate risks can be impaired when they take acetaminophen. While the effects might be slight, they're definitely worth noting, given acetaminophen is the most common drug ingredient in America, found in over 600 different kinds of over-the-counter and prescription medicines.

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Overall, however, based on an average of results across the various tests, the team concludes that there is a significant relationship between taking acetaminophen and choosing more risk, even if the observed effect can be slight.

That said, they acknowledge the drug's apparent effects on risk-taking behavior could also be interpreted via other kinds of psychological processes, such as reduced anxiety, perhaps.