Gene-Editing Human Embryos Is Ethical

Bioethicists and scientists who say otherwise are wrong.

By Ronald Bailey
Reason.com
Originally published May 1, 2015

Here are two excerpts:

The Chinese scientists essentially ignored recent calls for a moratorium on editing human reproductive cells and embryos. The month before their paper appeared, Science recommended that such research be "strongly discourage[d]" while the "societal, environmental, and ethical implications of such activity are discussed among scientific and governmental organizations." Meanwhile, Nature had editorialized that "genome editing in human embryos using current technologies could have unpredictable effects on future generations. This makes it dangerous and ethically unacceptable....At this early stage, scientists should agree not to modify the DNA of human reproductive cells." Some 40 countries have preemptively banned germline genetic engineering. (The United States is not among them.)

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In what terrible bioethical violations did the Chinese researchers engage? None. The embryos were grown to the eight-cell stage, and none of them could ever have developed into babies. No germline cells with any potential to develop into people were modified. Of the 71 embryos that survived the experiment, 54 were genetically tested. Of these, 28 embryos had the target gene "spliced." Only four contained all of the replacement genetic material, and even those were mosaics—that is, not every cell had been modified.

The entire article is here.

U.S. high court won't review federal embryonic stem cell funds

By Terry Baynes
Reuters
Originally posted on January 7, 2013

The U.S. Supreme Court on Monday refused to review a challenge to federal funding of human embryonic stem cell research brought by two researchers who said the U.S. National Institutes of Health rules on such studies violate federal law.

The decision brings an end to a lawsuit that had threatened to hamper stem cell research after a district court judge blocked the taxpayer funding in 2010. But some observers expected the Supreme Court would decline the take the case after an appeals court ruled that the funding could continue.

U.S. law prohibits the NIH from funding the creation of human embryos for research or research in which human embryos are destroyed, but leaves room for debate over whether that includes work with human embryonic stem cells.

Opponents of such research, including many religious conservatives, have argued that it is unacceptable because it destroys human embryos.

Scientists hope to be able to use stem cells to find treatments for spinal cord injuries, cancer, diabetes and diseases such as Alzheimer's and Parkinson's.

The entire story is here.