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Welcome to the nexus of ethics, psychology, morality, technology, health care, and philosophy
Showing posts with label Genetic Research. Show all posts
Showing posts with label Genetic Research. Show all posts

Wednesday, January 24, 2018

The Moral Fabric and Social Norms

AEI Political Report
Volume 14, Issue 1
January 2018

A large majority now, as in the past, say moral values in the country are getting worse. Social conservatives, moderates, and liberals agree. At the same time, however, as these pages show, people accept some behaviors once thought wrong. Later in this issue, we look at polls on women’s experiences with sexual harassment, a topic which has drawn public scrutiny following recent allegations of misconduct against high profile individuals.

Q: Right now, do you think . . . ?




Tuesday, January 3, 2017

Should the 14-day limit on embryo research be extended?

by Philip Ball
Prospect Magazine
Originally published December 12, 2016

Here is an excerpt:

That limit has remained in place ever since. But now some scientists believe it should be extended to 28 days. These proposals were discussed on 7th December at a meeting in London organised by charity the Progress Educational Trust. It marked the beginning of what seems likely to be a broad and extended discussion among scientists, bioethicists, fertility specialists, religious leaders and others who have a stake in the moral, legal and scientific status of the human embryo.

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So the 14-day embryo has begun the process that leads to the laying down of the human body plan—but only just. A key stage, called gastrulation, begins around day 16: this is when the embryo acquires a three-layered structure, the precursor to the appearance of different body-tissue types. So the time between day 14 and day 28 sees the embryo progress through some crucial stages of development, and understanding the details of what goes on, such as the genetic changes involved, should provide a wealth of information that might offer insights into human health, disease and malformation. Much of what we know about these stages at present comes from studies of mice—but as several of the speakers acknowledged, there are some important differences between mice and men.

This is why it looks so enticing for cell biologists and geneticists to investigate the post-14-day embryo. But should that be allowed by a change in the law?

The article is here.

Wednesday, December 16, 2015

Where to Draw the Line on Gene-Editing Technology

New techniques that could make germline genetic engineering unprecedentedly easy are forcing policymakers to confront the ethical implications of moving forward

By Jonathan D. Moreno
Scientific American
November 30, 2015

The biologists have done it again. Not so long ago it was cloning and embryonic stem cells that challenged moral imagination. These days all eyes are on a powerful new technique for engineering or “editing” DNA. Relatively easy to learn and to use, CRISPR has forced scientists, ethicists and policymakers to reconsider one of the few seeming red lines in experimental biology: the difference between genetically modifying an individual’s somatic cells and engineering the germline that will be transmitted to future generations. Instead of genetic engineering for one person why not eliminate that disease trait from all of her or his descendants?

This week, the U.S. National Academy of Sciences, the Chinese Academy of Sciences, and the U.K. Royal Society are trying to find ways to redraw that red line. And redraw it in a way that allows the technology to help and not to hurt humanity. Perhaps the hardest but most critical part of the ethical challenge: doing that in a way that doesn’t go down a dark path of “improvements” to the human race.

The article is here.

Tuesday, September 29, 2015

Modernizing Human Subjects Research Protections: Informed Consent for Genetic Research

Written by Nicolle Strand
blog.bioethics.gov
September 24, 2015

Here is an excerpt:

Despite these challenges, the Commission emphasized the importance of obtaining fully informed consent from all participants. Being asked to provide informed consent about the use of their data, the Commission argued, conveys respect to participants, separate and apart from their interest in preventing the unauthorized use or disclosure of their data. In other words—there is value to informed consent in and of itself, as it respects autonomy and personhood.

The entire blog post is here.

Note: The blog posts are short.  These are excellent resources from the Presidential Commission for the Study of Bioethical Issues.