The New Normal: How the definition of disease impacts enhancement

By Ray Purcell

The Neuroethics Blog

Originally posted July 24, 2014

Here is an excerpt:

Why does the definition of disease matter? Enhancement is typically defined relative to normal abilities. Anjan Chatterjee of the University of Pennsylvania suggested that “Therapy is treating disease, whereas enhancement is improving “normal” abilities. Most people would probably agree that therapy is desirable. By contrast, enhancing normal abilities gives pause to many.” However, many neuroethicists have wrestled with clearly defining enhancement. The director of Emory’s Center for Ethics, Paul Root Wolpe argued (2002) that the enhancement debate centers on the ability of substances or therapeutics to directly affect the brain in ways that are not necessary to restore health and, certainly, to date the cognitive enhancement debate has focused primarily on pharmaceuticals, many of which are approved to treat disorders but can have effects on healthy individuals as well. Perhaps the best examples of this are methylphenidate (Ritalin) and modafinil (Provigil) which are prescribed for attention deficit hyperactivity disorder (ADHD) and narcolepsy respectively, but are increasingly being used by students and professionals to boost cognitive performance at school and in the workplace. 

The entire blog post is here.

Testosterone Inhibits Trust but Promotes Reciprocity

By Maarten A. S. Boksem and others
Psychological Science 0956797613495063, first published on September 26, 2013

Abstract

The steroid hormone testosterone has been associated with behavior intended to obtain or maintain high social status. Although such behavior is typically characterized as aggressive and competitive, it is clear that high social status is achieved and maintained not only through antisocial behavior but also through prosocial behavior. In the present experiment, we investigated the impact of testosterone administration on trust and reciprocity using a double-blind randomized control design. We found that a single dose of 0.5 mg of testosterone decreased trust but increased generosity when repaying trust. These findings suggest that testosterone may mediate different types of status-seeking behavior. It may increase competitive, potentially aggressive, and antisocial behavior when social challenges and threats (i.e., abuse of trust and betrayal) need to be considered; however, it may promote prosocial behavior in the absence of these threats, when high status and good reputation may be best served by prosocial behavior.

The entire article is here, hiding behind a paywall.