British Medical Journal
Originally released January 17, 2017
Here is an excerpt:
More than half (58%) of principal investigators had financial ties to the drug industry - including travel expenses, honorariums, payment for advisory work, or stock ownership.
The results show that trials authored by principal investigators with financial ties to drug manufacturers were more likely than other trials to report favourable results.
Even after accounting for factors that may have affected the results, such as funding source and sample size, financial ties were still significantly associated with positive study outcomes.
The authors point to possible mechanisms linking industry funding, financial ties, and trial results such as bias by selective outcome reporting, lack of publication, and inappropriate analyses.
The pressor is here.